An anonymous reader quotes a report from the Associated Press: U.S. health officials on Friday endorsed the first blood test that can help diagnose Alzheimer's and identify patients who may benefit from drugs that can modestly slow the memory-destroying disease. The test can aid doctors in determining whether a patient's memory problems are due to Alzheimer's or a number of other medical conditions that can cause cognitive difficulties. The Food and Drug Administration cleared it for patients 55 and older who are showing early signs of the disease. The new test, from Fujirebio Diagnostics, Inc., identifies a sticky brain plaque, known as beta-amyloid, that is a key marker for Alzheimer's. Previously, the only FDA-approved methods for detecting amyloid were invasive tests of spinal fluid or expensive PET scans. The lower costs and convenience of a blood test could also help expand use of two new drugs, Leqembi and Kisunla, which have been shown to slightly slow the progression of Alzheimer's by clearing amyloid from the brain. Doctors are required to test patients for the plaque before prescribing the drugs, which require regular IV infusions. [...] A number of specialty hospitals and laboratories have already developed their own in-house tests for amyloid in recent years. But those tests aren't reviewed by the FDA and generally aren't covered by insurance. Doctors have also had little data to judge which tests are reliable and accurate, leading to an unregulated marketplace that some have called a "wild west." Several larger diagnostic and drug companies are also developing their own tests for FDA approval, including Roche, Eli Lilly and C2N Diagnostics. The tests can only be ordered by a doctor and aren't intended for people who don't yet have any symptoms.

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Microsoft has released Command Palette, an enhanced version of its PowerToys Run launcher introduced five years ago. The utility, aimed at power users and developers, provides quick access to applications, files, calculations, and system commands through a Spotlight-like interface. Command Palette integrates the previously separate Window Walker functionality for switching between open windows and supports launching command prompts, executing web searches, and navigating folder structures. Unlike its predecessor, the new launcher offers full customization via extensions, allowing users to implement additional commands beyond default capabilities. Available through the PowerToys application since early April, Command Palette can be triggered using Win+Alt+Space after installation

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Walmart is preparing for a future where AI agents shop on behalf of consumers by adapting its systems to serve both humans and autonomous bots. As major players like Visa and PayPal also invest in agentic commerce, Walmart is positioning itself as a leader by developing its own AI agents and supporting broader industry integration. PYMNTS reports: Instead of scrolling through ads or comparing product reviews, future consumers may rely on digital assistants, like OpenAI's Operator, to manage their shopping lists, from replenishing household essentials to selecting the best TV based on personal preferences, according to the report (paywalled). "It will be different," Walmart U.S. Chief Technology Officer Hari Vasudev said, per the report. "Advertising will have to evolve." The emergence of AI-generated summaries in search results has already altered the way consumers gather product information, the report said. However, autonomous shopping agents represent a bigger transformation. These bots could not only find products but also finalize purchases, including payments, without the user ever lifting a finger. [...] Retail experts say agentic commerce will require companies to overhaul how they market and present their products online, the WSJ report said. They may need to redesign product pages and pricing strategies to cater to algorithmic buyers. The customer relationship could shift away from retailers if purchases are completed through third-party agents. [...] To prepare, Walmart is developing its own AI shopping agents, accessible through its website and app, according to the WSJ report. These bots can already handle basic tasks like reordering groceries, and they're being trained to respond to broader prompts, such as planning a themed birthday party. Walmart is working toward a future in which outside agents can seamlessly communicate with the retailer's own systems -- something Vasudev told the WSJ he expects to be governed by industry-wide protocols that are still under development. [...] Third-party shopping bots may also act independently, crawling retailers' websites much like consumers browse stores without engaging sales associates, the WSJ report said. In those cases, the retailer has little control over how its products are evaluated. Whether consumers instruct their AI to shop specifically at Walmart or ask for the best deal available, the outcomes will increasingly be shaped by algorithms, per the report. Operator, for example, considers search ranking, sponsored content and user preferences when making recommendations. That's a far cry from how humans shop. Bots don't respond to eye-catching visuals or emotionally driven branding in the same way people do. This means retailers must optimize their content not just for people but for machine readers as well, the report said. Pricing strategies could also shift as companies may need to make rapid pricing decisions and determine whether it's worth offering AI agents exclusive discounts to keep them from choosing a competitor's lower-priced item, according to the report.

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In an exclusive interview with the BBC, AWS CEO Matt Garman said the UK must expand nuclear energy to meet the soaring electricity demands of AI-driven data centers. From the report: Amazon Web Services (AWS), which is part of the retail giant Amazon, plans to spend 8 billion pounds on new data centers in the UK over the next four years. Matt Garman, chief executive of AWS, told the BBC nuclear is a "great solution" to data centres' energy needs as "an excellent source of zero carbon, 24/7 power." AWS is the single largest corporate buyer of renewable energy in the world and has funded more than 40 renewable solar and wind farm projects in the UK. The UK's 500 data centres currently consume 2.5% of all electricity in the UK, while Ireland's 80 hoover up 21% of the country's total power, with those numbers projected to hit 6% and 30% respectively by 2030. The body that runs the UK's power grid estimates that by 2050 data centers alone will use nearly as much energy as all industrial users consume today. In an exclusive interview with the BBC, Matt Garman said that future energy needs were central to AWS planning process. "It's something we plan many years out," he said. "We invest ahead. I think the world is going to have to build new technologies. I believe nuclear is a big part of that particularly as we look 10 years out."

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